Webinar: Prof. Lehana Thabane - Getting Pilot and Feasibility Studies Right: Design, Analysis, and Reporting
Event Details
Pilot and feasibility studies for phase III trials are primarily designed to provide feasibility evidence for large trials intended to generate evidence on effects of benefit and harm of a drug or intervention. Conducting a pilot prior to the main study can enhance the likelihood of success of the main study and potentially help to avoid doomed main studies. This presentation will cover some key aspects of pilot studies for phase III trials including past practice history; the general reasons for conducting a pilot study; the relationships between pilot studies, and proof-of-concept studies; the challenges of and misconceptions about pilot studies; the criteria for evaluating the success of a pilot study; frequently asked questions about pilot studies; some ethical aspects related to pilot studies; and ongoing efforts to improve current and future practice
Speaker:
Dr. Lehana Thabane is a Vice President of Research at St Joseph’s Healthcare—Hamilton and St Joseph’s Health System; Scientific Director of the Research Institute at St Joseph’s Healthcare; Distinguished Professor University in the Department of Health Research Methods, Evidence, and Impact at McMaster University. He is a Fellow of the World Academy of Science, the Royal Society of Canada, the African Academy of Sciences, the American Statistical Association, the Society for Clinical Trials, the Canadian Academy of Health Sciences, and Honorary Foreign Associate Member of the Academy of Science of South Africa. He is the Past President of the Society for Clinical Trials 2022-2023. He is the recipient of the 2022 of the Statistical Society of Canada Award for Impact of Applied and Collaborative Work. He was a recipient of an honorary degree from Stellenbosch University in South Africa in December 2023 for his contribution to clinical trial methodology.
Dr Thabane is the Emeritus Founding Editor-in-Chief of the journal Pilot and Feasibility Studies; and he is a member of the editorial board for many journals including Trials, and BMJ Open. He has co-authored over 1300 peer-reviewed manuscripts leading to significant contributions and transformation of science, healthcare, and delivery of care in many clinical areas. Having mentored over 200 graduate students and junior faculty, Dr Thabane has won several teaching and mentorship awards for his commitment to building capacity in health research and nurturing the next generation of researchers
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