Upcoming Events
The HRB-TMRN delivers two streams of training nationally across the areas of Trials Methodology and Trials Essentials. Training is delivered both in-person and online, in the format of webinars / seminars, workshops, study days, short courses and Symposia. We welcome feedback from our attendees at every event, to help shape the training we offer.
march 2024
28mar11:00 am12:00 pmPractical Guidance on EU CRT and CTIs: Session 3 (Online)
Event Details
To apply and / or find out more, click here
Event Details
To apply and / or find out more, click here
Time
(Thursday) 11:00 am – 12:00 pm
Organizer
april 2024
Event Details
Click here to register Randomised controlled trials are susceptible to poor participant recruitment and retention. Studies Within A Trial (SWATs) are the strongest methods for testing the effectiveness
Event Details
Randomised controlled trials are susceptible to poor participant recruitment and retention. Studies Within A Trial (SWATs) are the strongest methods for testing the effectiveness of strategies to improve recruitment and retention. However, relatively few of these have been conducted. The PROMoting THE Use of Studies Within A Trial (PROMETHEUS) programme aimed facilitated 42 SWATs evaluating recruitment or retention strategies across 31 host trials. In this webinar, we will share our experiences of delivering the PROMETHEUS programme, and the lessons learnt for undertaking randomised SWATs
Dr Adwoa Parker is a trial methodologist, a UK National Institute of Health Research (NIHR) Advanced Fellow and leads the Trial Forge Studies Within A Trial (SWATs) Centre at The University of York (UK). SWATs are self-contained studies embedded within ongoing randomised trials that aim to generate evidence to improve the design and delivery of future trials. Adwoa’s Advanced Fellowship, ‘IMPLEMENT SWATs’, funded for 10 years, aims to use implementation science and SWATs to improve evidence-informed participant recruitment and retention in trials. Adwoa was previously co-investigator and Programme Manager on PROMETHEUS, a major programme of research funded by the UK Medical Research Council (MRC) to facilitate the routine embedding of a recruitment or retention SWAT in ongoing randomised controlled trials. PROMETHEUS produced the largest body of SWAT activity in the world.
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Time
(Thursday) 1:00 pm – 2:00 pm
Event Details
Click here to register TMRP webinar – presented by Rosalie Hayes and Nishat Halim on behalf of the UK Trial Managers’ Network The ILANA study – using study recruitment
Event Details
TMRP webinar – presented by Rosalie Hayes and Nishat Halim on behalf of the UK Trial Managers’ Network
The ILANA study – using study recruitment targets to promote equity in clinical care for women, racially minoritised people and older people living with HIV in the UK
Rapid advances in HIV treatment over the last few decades have recently culminated in the development and approval of a novel, long-acting injectable therapy for HIV treatment. Long-acting Cabotegravir and Rilpivirine (CAB+RPV LA) allows people living with HIV to receive 2-monthly injectable treatment, rather than daily pills. However women, racially minoritised people and older people are chronically under-represented in HIV clinical trials. The ILANA implementation study, which explores the acceptability and feasibility of CAB+RPV LA delivered in clinical and community settings in England, provided an opportunity to promote inclusion in HIV research and equity in HIV clinical care through the use of study recruitment targets. In this talk, ILANA Trial Manager Nishat Halim and qualitative researcher Rosalie Hayes will discuss the thinking behind the study recruitment targets, how they worked in practice, and the impact they have had on the study findings so far.
Please note, you need to register for this event in order to receive an email invitation to join the session. Registrations are limited to 250 attendees and places will be offered on a first come first served basis.
This webinar will be hosted via MS Teams. You will need access to the web and sound facilities in order to view the webinar.
A recording of the webinar will be made available after the event. Previous recordings can be found here: https://www.methodologyhubs.mrc.ac.uk/about/webinar/
UKTMN members also have access to recordings via the UKTMN YouTube channel.
If you have any questions regarding this event or wish to cancel your place, please email uktmn@nottingham.ac.uk
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Time
(Wednesday) 11:00 am – 12:00 pm
24apr10:00 am4:00 pmStatistical Power and Sample Size in Clinical Trials (In-person)
Event Details
To register, click here Contact us at hrb-tmrn@universityofgalway.ie for more information
Event Details
Time
(Wednesday) 10:00 am – 4:00 pm
Location
Durkan Theatre, Trinity Translational Medicine Institute, St James' Hospital
Organizer
may 2024
02may1:00 pm5:00 pmDeliberating Ethics in Trials: Scope and necessity of ethical oversight (Online)
Event Details
Click here to register The HRB Clinical Research Facility at University College Cork are delighted to announce this half day event in partnership with the HRB-TMRN.
Event Details
The HRB Clinical Research Facility at University College Cork are delighted to announce this half day event in partnership with the HRB-TMRN. This course will look at the scope and necessity of ethical oversight in trials.
For full programme, click here
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Time
(Thursday) 1:00 pm – 5:00 pm
Event Details
For applied health researchers with basic training in statistics (e.g. regression). Attendees will learn how to: Design more effective, affordable, scalable and efficient complex interventions Utilise novel experimental
Event Details
For applied health researchers with basic training in statistics (e.g. regression). Attendees will learn how to:
- Design more effective, affordable, scalable and efficient complex interventions
- Utilise novel experimental designs to optimise complex interventions
- Overcome analysis and delivery challenges
Location: In-person at the University of Leeds,
Date: 7th – 9th May 2024
Fee: £750 (including refreshments and lunch)
Reserve your place now by contacting Wendy Hobson at w.Hobson@leeds.ac.uk
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Time
may 7 (Tuesday) – 9 (Thursday)
Location
University of Leeds
09may9:00 am4:00 pmHRB NCTO – International Clinical Trial Day Conference (In-person)
Event Details
The HRB National Clinical Trials Office are delighted to announce that registration for the annual International Clinical Trial Day (ICTD) Conference is now open. It will be an
Event Details
The HRB National Clinical Trials Office are delighted to announce that registration for the annual International Clinical Trial Day (ICTD) Conference is now open. It will be an in-person event and the venue will be O’Reilly Hall, UCD, Belfield, Dublin 4 and occurs on May 9th. The Keynote speaker this year is Lord James O’Shaughnessy, whose review of “Commercial clinical trials in the UK” was published in 2023 – link to full report https://shorturl.at/jkvL9.
For further information and to access the related Eventbrite link, please click on this link to go to our dedicated website page.
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Time
(Thursday) 9:00 am – 4:00 pm
Location
O'Reilly Hall, UCD, Belfield, Dublin 4
Event Details
Click here to register With rapid increase in the use of artificial intelligence in healthcare, the need for thoughtful, ethical, and impactful application to support clinical trials is
Event Details
With rapid increase in the use of artificial intelligence in healthcare, the need for thoughtful, ethical, and impactful application to support clinical trials is imperative. This webinar will explore the current and future applications of artificial intelligence for clinical trial design, conduct, and reporting, with a focus on the ethical considerations of these new technologies.
Dr Danielle Bitterman is an Assistant Professor in the Department of Radiation Oncology at Brigham and Women’s Hospital/Dana-Farber Cancer Institute, Harvard Medical School. Dr. Bitterman is a physician-scientist whose expertise is in artificial intelligence and natural language processing. Her research is focused on improving data driven cancer care and her laboratory develops natural language processing methods that process high volumes of data from electronic health records to inform care and facilitate communication.
Dr. Subha Perni is an Assistant Professor in the Department of Radiation Oncology at MD Anderson Cancer Center. Dr. Perni specializes in the care of patients with central nervous system malignancies. Her research focuses on designing prospective patient-centered clinical trials incorporating advanced technology and imaging with the aim of improving quality of life and outcomes for these patients. She has additional expertise in ethics and decision-making.
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Time
(Thursday) 1:00 pm – 2:00 pm
24may10:00 am4:00 pmRapid Research Methods Applicable in Clinical Trials (In-person)
Event Details
Hosted by QUESTS, HRB-TMRN & RREAL@UCL To register, click here Contact us at hrb-tmrn@universityofgalway.ie for more information
Event Details
Hosted by QUESTS, HRB-TMRN & RREAL@UCL
To register, click here
Contact us at hrb-tmrn@universityofgalway.ie for more information
Time
(Friday) 10:00 am – 4:00 pm
Location
University of Galway, Galway City
Organizer
june 2024
05jun10:00 am5:00 pmMethods of Analysis for Different Estimands (In-person)
Event Details
Estimands are becoming widely used in randomised trials. This MRC-NIHR-TMRP funded course covers the statistical methods that can be used to estimate different estimands. We will cover methods for each
Event Details
Estimands are becoming widely used in randomised trials. This MRC-NIHR-TMRP funded course covers the statistical methods that can be used to estimate different estimands. We will cover methods for each intercurrent event strategy (treatment policy, composite, while-on-treatment, principal stratum, and hypothetical), and provide practical examples along with statistical code in Stata and R to implement the different estimators.
Facilitators
- Brennan Kahan, MRC Clinical Trials Unit at UCL
- Suzie Cro, Imperial Clinical Trials Unit
- Ian White, MRC Clinical Trials Unit at UCL
- Richard Emsley, Kings Clinical Trials Unit
- Darren Dahly, HRB Clinical Research Facility – University College Cork
- Tra My Pham, MRC Clinical Trials Unit at UCL
- Beatriz Goulao, Health Services Research Unit, University of Aberdeen
Course aims
By the end of this workshop, participants will understand:
- The interpretation of the different intercurrent event strategies
- Which estimators can be used for different intercurrent event strategies, along with their assumptions
- How to choose between different estimators for a given trial
- How to implement the estimators in Stata or R
Target audience
- Applied statisticians working on randomised trials
Software required
All participants will need their own laptop running a recent version of either Stata or R.
Fees
The course is free. However, it is likely to be oversubscribed, in this case the attendees will be selected based on their registration.
Location
MRC Clinical Trials Unit at UCL, 90 High Holborn, London
To register, click here
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Time
(Wednesday) 10:00 am – 5:00 pm
Location
MRC Clinical Trials Unit at UCL, 90 High Holborn, London
06jun10:00 am4:00 pmTrial Steering Committee Training Workshop (Online)
Event Details
To register, click here Co-hosted with the MRC-NIHR Trials Methodology Research Partnership and the Irish Critical
Event Details
To register, click here
Co-hosted with the MRC-NIHR Trials Methodology Research Partnership and the Irish Critical Care Clinical Trials Network
Schedule: TBC
Contact us at hrb-tmrn@universityofgalway.ie if you have any questions about this event.
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Time
(Thursday) 10:00 am – 4:00 pm
july 2024
Event Details
Click here to register TMRP webinar – presented by Dr Kerry Dwan (Liverpool School of Tropical Medicine), Professor Car on behalf of the MRC HTMR Study publication bias and
Event Details
TMRP webinar – presented by Dr Kerry Dwan (Liverpool School of Tropical Medicine), Professor Car on behalf of the MRC HTMR
Study publication bias and outcome reporting bias have been recognised as a potential threat to the validity of meta-analysis and can make the readily available evidence unreliable for decision making. Statistical Analysis Plans have the potential to reduce outcome reporting bias.
In an update to a systematic review, we will summarise the evidence from cohort studies that have assessed study publication bias or outcome reporting bias in randomised controlled trials. Twenty-nine studies were eligible of which eleven were newly identified in this update. Eleven groups followed a cohort of trial through from protocol approval to information regarding publication of outcomes and investigated outcome reporting bias. Findings will be presented.
Guidelines for the content of statistical analysis plans in clinical trials were published in 2018. An analysis of 62 citations in early 2020 revealed a steady increase in the use of the guidance. Findings from an updated analysis of a further 168 citations by the end of 2023 will be presented.
The implications from contrasting the results from these two projects will be discussed.
Please note, you need to register for this event in order to receive an email invitation to join the session. Registrations are limited to 250 attendees and places will be offered on a first come first served basis.
This webinar will be hosted via MS Teams. You will need access to the web and sound facilities in order to view the webinar.
A recording of the webinar will be made available after the event. Previous recordings can be found here: https://www.methodologyhubs.mrc.ac.uk/about/webinar/
UKTMN members also have access to recordings via the UKTMN YouTube channel.
If you have any questions regarding this event or wish to cancel your place, please email uktmn@nottingham.ac.uk
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Time
(Wednesday) 1:00 pm – 2:00 pm
september 2024
09sep(sep 9)9:00 am11(sep 11)4:00 pmBOASTiC Surgical Trial Training Course (In-person)
Event Details
The RCSI-NSRSC in partnership with the HRB-TMRN and the UK Surgical Trials Units are delighted to host this year’s BOASTiC for the first time in Ireland. The course is accredited
Event Details
The RCSI-NSRSC in partnership with the HRB-TMRN and the UK Surgical Trials Units are delighted to host this year’s BOASTiC for the first time in Ireland. The course is accredited by RCSEng and will be delivered by well-renowned local and international experts in surgical trials and trial methodology. Students work collaboratively to learn how to design and conduct randomised controlled trials in surgery that answer research questions of relevance to surgeons and patients. Find further information here or email Katie Chegwin.
Date: 9-11 September 2024
Location: RCSI Dublin
Course fee: €300
Application closing date: 8 March 2024
Please note registration does not guarantee a place. Applications will be reviewed after the closing date and you will be notified if you have been offered a place on the course. Fee payment will be requested to secure your place at that point.
To apply, click here
Contact us at hrb-tmrn@universityofgalway.ie for more information
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Time
9 (Monday) 9:00 am – 11 (Wednesday) 4:00 pm
Location
Royal College of Surgeons Ireland
123 St. Stephen’s Green
Event Details
To register, click here The International Clinical Trials Methodology Conference 2024 promises to be a unique opportunity
Event Details
To register, click here
The International Clinical Trials Methodology Conference 2024 promises to be a unique opportunity for those working in clinical trials to meet and discuss the current issues within trials and methodology. The event will showcase the very latest in trials methodology research and offer plenty of valuable opportunities for networking. A diverse programme will be prepared by the Scientific Committee and Education Committee, which promises to make this a highly rewarding and enjoyable meeting for all.
The 7th ICTMC Conference will be held at the Edinburgh International Conference Centre (EICC) from 30 September – 3 October 2024 in Edinburgh! The venue is situated in the heart of the historic city of Edinburgh and it is just a short walk away from Princes Street, Edinburgh Castle and the Royal Mile.
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Time
September 30 (Monday) 9:00 am – October 3 (Thursday) 4:00 pm
october 2024
Event Details
To register, click here The International Clinical Trials Methodology Conference 2024 promises to be a unique opportunity
Event Details
To register, click here
The International Clinical Trials Methodology Conference 2024 promises to be a unique opportunity for those working in clinical trials to meet and discuss the current issues within trials and methodology. The event will showcase the very latest in trials methodology research and offer plenty of valuable opportunities for networking. A diverse programme will be prepared by the Scientific Committee and Education Committee, which promises to make this a highly rewarding and enjoyable meeting for all.
The 7th ICTMC Conference will be held at the Edinburgh International Conference Centre (EICC) from 30 September – 3 October 2024 in Edinburgh! The venue is situated in the heart of the historic city of Edinburgh and it is just a short walk away from Princes Street, Edinburgh Castle and the Royal Mile.
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Time
September 30 (Monday) 9:00 am – October 3 (Thursday) 4:00 pm
Our Network operates across five University Partners,
each leading the way in trials methodology research and training