Core Outcome Sets

Developing a core outcome set (COS) for clinical studies of prepregnancy care for women with pregestational diabetes mellitus.
The aim of this study was to develop a core outcome set (COS) for trials and other studies evaluating the effectiveness of prepregnancy care for women with pregestational (pre-existing) diabetes mellitus.
Developing a core outcome set (COS) for clinical trials in intrauterine growth restriction
Developing a COS for use in all studies of the screening, prevention and treatment of intrauterine growth restriction is timely and important.
Developing a core outcome set (COS) for intrapartum fetal assessment
Developing a COS for use in all studies of interventions for assessment of fetal wellbeing in labour is timely and important. The use of the COS as a minimum across the field of intrapartum fetal assessment would allow for the results of trials and other studies to be effectively compared, contrasted and combined, as appropriate.
Salutogenic Intrapartum Core Outcomes (SIPCO): Identification of a minimum dataset using an international eDelphi consensus process
Using a list of salutogenically-focused reported outcomes identified in a systematic review of systematic reviews of intrapartum interventions, conducted by the principal investigators to the project, and others, we propose to develop, through expert opinion and consensus, a set of salutogenic intrapartum core outcomes (SIPCO) for use in maternity care research and daily practice.
Developing a core outcome set (COS) for clinical trials in GDM
The majority of clinical trials in gestational diabetes mellitus (GDM) have been published in the last ten years suggesting a growing interest in research on this important topic. However, prioritization of outcomes for use in studies on GDM has been confined to medication or birth management. For this reason, developing a COS for use in all studies of the screening, prevention and treatment of GDM is timely and important.
Developing a core outcome set (COS) for clinical trials on interventions for the detection and management of reduced fetal movements in pregnancy
In recent years there has been a renewed interest in the topic of fetal movements in pregnancy, with numerous studies on aspects of both the detection and management of RFM in pregnancy appearing in the literature, including associated calls for larger randomised trials.
The development of a core outcome set for interventions in the treatment of uncomplicated urinary tract infections (UTI’s) in adult patients.
In order to address the inappropriate use of antimicrobials in the treatment of uncomplicated UTIs in primary care, further research needs to be undertaken in this area. However, inconsistency in the choice of outcomes reported have resulted in substantial challenges in synthesising evidence, ultimately limiting the capability to influence practice and policy
Core Outcome Sets for Prevention and Treatment of Postpartum Haemorrhage
Postpartum Haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Interventions for its prevention and treatment have been the subject of a large number of trials, but evidence is difficult to interpret due to heterogeneity in endpoints. We propose the development of Core Outcomes Sets (COS) for (1) prevention and (2) treatment of PPH by consulting relevant stakeholders using a Delphi survey.
Metabolic follow up at one year and beyond of women with gestational diabetes treated with insulin and/or oral hypoglycaemic agents: identification of a core outcomes set using a Delphi survey
Development of a core outcome set for trials on induction of labour (COSIOL): An international multi-stakeholder Delphi study
Developing a Core Outcome Set for Childhood Obesity Prevention: A Systematic Review
A core outcome set for adult cardiac surgery trials: A consensus study
Heterogeneity of wound outcome measures in RCTs of treatments for VLUs: a systematic review

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