Study within a Trial (SWAT)

To date, the HRB-TMRN has funded nine SWATs investing €135,000 in developing this initiative nationally. In 2022 the network will provide further funding for two SWAT awards. These awards are worth up to €10,000 (to include 25% institutional overheads of direct project costs) and will provide for the implementation of a self-contained methodological research study in a planned or an existing randomised trial. This funding is available to research teams in University College Cork, NUI Galway, Trinity College Dublin, University of Limerick and University College Dublin.

Opening Date: September 24th 2021 Closing Date: March 25th 2022

NUI Galway
Trinity Dublin

Scope of the current call

The scope of the current call is to facilitate the embedding of a methodology research study within a planned or ongoing trial. The SWAT should address a methodology research question on any aspect of the trial, for example: design, conduct, analysis, reporting or dissemination of trials, for which there is current uncertainty. Novel methodology questions are welcome, however applicants may also choose to repeat a SWAT in a new trial setting. A full listing of published SWAT protocols are available on the MRC-HTMR All-Ireland Hub website.

Number of awards

Two awards of up to €10,000 (to include 25% institutional overheads of direct project costs) for up to 12 months in duration will be awarded in 2022. Applicants must be from one of the four eligible institutions; NUI Galway, UCC, TCD, UL and UCD.

Who should apply?

Trial investigator teams working on a planned or ongoing randomised trial are invited to apply. There are no eligibility restrictions for the lead applicant (e.g. previous grant holder) and early stage career researchers are welcome to apply, provided that the trial Principal Investigator for the host trial within which the proposed SWAT is embedded supports the application and appropriate mentoring arrangements are in place.

Eligibility criteria

  • The application must include evidence from host institution of provision for funding for the ongoing trial (letter from research office). In the case where a trial is not funded and does not need funding to proceed, this will need justification.
  • Applications must provide evidence of mentoring arrangements (where appropriate) to provide academic and clinical/practice-based support.
  • Applicants must have a collaborator from the MRC/NIHR- Trials Methodology Research Partnership (MRC/NIHR-TMRP) (assistance in identifying suitable collaborators can be provided).


Queries relating to this application can be submitted by email to, please include SWAT FUNDING 2022 in the subject line. All application forms must be submitted by email, along with relevant documentation to by the deadline listed above.

SWAT Repository

Condition of award: The successful SWAT must be registered on the MRC Northern Ireland Hub for Trials Methodology SWAT Repository, which is an online database of ongoing SWATs.

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